Zinc Citrate
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Zinc Citrate

Minerals & Trace Elements Nutritional Enhancers
546-46-3
C₆H₈O₇·1.5 Zn (or C₁₂H₁₀O₁₄Zn₃·2H₂O for trihydrate)
$4.21 ~ $6.31
Food
Free sample from 100g(NF)
One unit of:25kg/bag
25kg/bag
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Product Info

What is Zinc Citrate?

Zinc Citrate is the zinc salt of citric acid, utilized primarily as a highly bioavailable nutritional supplement to fortify foods and beverages with the essential mineral zinc.

How is Zinc Citrate made?

Step No. Production Stage Key Action Control Point & Note
1 Raw Material Preparation Dissolve high-purity citric acid in a measured volume of demineralized water within a glass-lined or stainless steel reactor. Control Point: Water quality and temperature; concentration of the citric acid solution.
Note: Ensure complete dissolution of citric acid to facilitate a smooth and uniform reaction.
2 Reaction & Synthesis Slowly add a high-purity zinc source (typically Zinc Oxide powder) to the citric acid solution under continuous, vigorous agitation. Control Point: Rate of addition of the zinc source to manage the exothermic reaction temperature. The pH level is constantly monitored to ensure the reaction progresses to completion.
3 Purification & Filtration Filter the resulting reaction slurry to remove any unreacted materials or insoluble impurities. Control Point: Filter integrity and pore size.
Note: This is a primary purification step to ensure the clarity and purity of the final product.
4 Crystallization Cool the clear, filtered solution under controlled conditions to induce the precipitation and crystallization of Zinc Citrate. Control Point: Cooling rate and final temperature.
Note: Slow, controlled cooling promotes the formation of larger, more uniform crystals, which are easier to separate and wash.
5 Separation & Washing Separate the precipitated Zinc Citrate crystals from the mother liquor using a centrifuge. The resulting crystal "cake" is then washed with demineralized water. Control Point: Centrifuge speed and duration; volume and purity of wash water.
Note: Washing is crucial to remove any remaining soluble impurities from the crystal surface.
6 Drying Dry the wet, washed Zinc Citrate cake in a controlled dryer (e.g., vacuum or fluid bed dryer) until the target moisture content is reached. Control Point: Drying temperature and time.
Note: This is a critical step to achieve product stability, prevent microbial growth, and meet the final moisture specification.
7 Milling & Sieving Mill the dried Zinc Citrate to a consistent, fine powder. Sieve the powder to ensure it meets the required particle size distribution. Control Point: Mill settings and sieve mesh size.
Note: This step ensures the final product has good flowability and meets customer physical requirements. Magnetic separators may be used to remove metal contaminants.
8 Final Quality Control & Packaging Sample and test the final powder against all specifications. Package the approved product into sealed, clean, food-grade containers. Control Point: Final analysis for zinc content (assay), purity, heavy metals (Pb, As, Cd), and microbiological limits.
Note: Proper packaging is essential to protect the product from moisture and contamination during storage and transport.

Technical Specifications

CAS Number 546-46-3
Chemical Formula C₆H₈O₇·1.5 Zn (or C₁₂H₁₀O₁₄Zn₃·2H₂O for trihydrate)
Solubility slightly soluble in water; soluble in dilute acids and alkali
Storage Conditions store in a cool, dry, light‑protected area
Shelf Life 36 Months

Applications & Usage

Common Applications:

used in dietary supplements
fortified foods
oral care products (toothpaste/mouthwash)

Mechanism of action:

Parameter Zinc Citrate
Functional Category Nutrient Fortificant; Flavor Enhancer; Sequestrant
Key Ingredients Zinc Citrate (Zinc salt of citric acid)
Mechanism of Action Provides a bioavailable source of elemental zinc, an essential cofactor for numerous enzymatic reactions vital for immune function, protein synthesis, and metabolism. The citrate anion can chelate pro-oxidant metal ions, preventing catalytic degradation of fats and vitamins. Contributes a mild, clean tartness.
Application Effect in Product Enriches foods and beverages like cereals, dairy alternatives, and nutritional supplements with dietary zinc. Helps mask metallic or bitter off-notes from other ingredients. Can improve shelf life and flavor stability by sequestering trace metals. Used in dental products to inhibit plaque and calculus formation.


Comparison:

Product Name Category/Type Key Features Strengths (vs peers) Weaknesses (vs peers) Best Use Cases Why Choose
Zinc Citrate Chelated Zinc Salt (Organic Acid) Zinc bound to citric acid. Well-absorbed form. Good bioavailability, often better tasting and more cost-effective than other chelated forms like picolinate. Absorption may be slightly lower than picolinate or glycinate; can still cause stomach upset in sensitive individuals. General daily supplementation for immune, skin, and hormonal health. A balanced choice offering good absorption and value without the harshness of inorganic salts.
Zinc Gluconate Chelated Zinc Salt (Organic Acid) Zinc bound to gluconic acid. Very common and widely studied. Widely available, cost-effective, and proven effective, especially in cold lozenges. Can have a noticeable metallic aftertaste; more likely to cause nausea than glycinate on an empty stomach. Short-term immune support (especially colds), general-purpose supplementation. For a readily available, well-researched, and affordable option.
Zinc Picolinate Amino Acid Chelate Zinc bound to picolinic acid, a natural chelator in the body. Considered to have one of the highest absorption and bioavailability rates. Typically the most expensive form per milligram of elemental zinc. Addressing significant deficiencies or for individuals with known malabsorption issues. When maximizing absorption is the primary goal and cost is not a major factor.
Zinc Glycinate (or Bisglycinate) Amino Acid Chelate Zinc bound to the amino acid glycine. High bioavailability and exceptionally gentle on the stomach, minimizing digestive side effects. Often more expensive than citrate and gluconate. Long-term supplementation, especially for individuals with sensitive stomachs. For a highly absorbed form that prioritizes digestive comfort and tolerability.
Zinc Sulfate Inorganic Zinc Salt A water-soluble, inorganic form of zinc. Very inexpensive and has been used in numerous clinical studies. Lower bioavailability and significantly more likely to cause stomach irritation and nausea. Prescription or clinical use for severe deficiency; some topical acne treatments. Under medical guidance for a specific condition or when cost is the absolute primary constraint.
Zinc Oxide Inorganic Zinc Compound Insoluble inorganic form of zinc. Common in sunscreens. Extremely low cost and shelf-stable. Poorly absorbed by the body compared to all other common forms; not ideal for supplementation. Primarily used topically (sunscreens, ointments) rather than for oral supplementation. Not recommended for oral use to correct a deficiency; choose another form for supplementation.

Technical Documents

Available Documentation

COA and monographs available

Safety Data Sheet (SDS)

MSDS available

Certificate of Analysis (COA)

Quality assurance documentation

Technical Data Sheet

Detailed technical specifications