Manganese Gluconate
Minerals & Trace Elements
Nutritional Enhancers
6485-39-8
C₁₂H₂₂MnO₁₄·2H₂O
$7.02 ~ $10.53
Food
Free sample from 100g(NF)
One unit of:25kg/barrel
One unit of:25kg/barrel
25kg/barrel
Product Info
What is Manganese Gluconate?
Manganese Gluconate is an organic mineral salt formed from manganese and gluconic acid, primarily used as a nutritional supplement to supply the essential trace mineral manganese in foods and dietary supplements.
How is Manganese Gluconate made?
| Step No. | Production Stage | Key Action | Control Point & Note |
|---|---|---|---|
| 1 | Synthesis & Reaction | React a high-purity manganese source, typically Manganese Carbonate, with a solution of Gluconic Acid in a jacketed glass-lined reactor containing purified water. | Control Point: Monitor and control the reaction temperature (e.g., 80-95°C) and pH level to ensure the reaction goes to completion. The quality of raw materials is critical. |
| 2 | Purification & Filtration | Filter the resulting solution through a press filter to remove any unreacted solids and insoluble impurities. Activated carbon may be added for decolorization before filtration. | Control Point: The clarity of the filtrate is a key indicator of successful purification. Ensure the filter integrity and appropriate pore size are maintained. |
| 3 | Concentration | Transfer the purified, clear solution to a vacuum evaporator. Heat the solution under reduced pressure to remove excess water and concentrate it to the point of supersaturation. | Control Point: Monitor the specific gravity or density of the solution. Vacuum concentration allows for water removal at lower temperatures, preventing product degradation. |
| 4 | Crystallization | Transfer the hot, concentrated solution to a crystallizer and cool it down under a controlled cooling profile. This induces the formation of Manganese Gluconate crystals. | Control Point: The rate of cooling directly impacts crystal size and purity. Slower cooling generally yields larger, more stable crystals. Agitation speed is also monitored. |
| 5 | Centrifugation & Washing | Separate the crystal slurry from the mother liquor using a centrifuge. The resulting crystal cake is then washed with a small amount of cold deionized water to remove surface impurities. | Control Point: Control centrifuge speed and time to achieve a specified residual moisture level in the wet cake. The wash step is vital for final purity. |
| 6 | Drying | Dry the washed, wet crystals in a suitable dryer (e.g., vacuum tray dryer or fluid bed dryer) at a controlled temperature until the moisture content reaches the specified limit. | Control Point: The drying temperature must be kept below the product's decomposition temperature. Monitor the Loss on Drying (LOD) until it meets the final specification. |
| 7 | Sizing & Blending | Mill the dried product if necessary and then pass it through a vibrating sieve to achieve a uniform particle size. The sieved lots are then blended for homogeneity. | Control Point: The sieve mesh size is critical for meeting customer particle size specifications. A metal detector is often used at this stage as a safety check. |
| 8 | Final QC & Packaging | A representative sample of the final blended batch is taken for full quality control analysis. Upon approval, the product is packaged into sealed, multi-layered, moisture-proof bags or drums. | Control Point: Final analysis must confirm compliance with all specifications, including assay (Manganese content), heavy metals, and microbiological limits. Packaging must be done in a controlled environment. |
Technical Specifications
| CAS Number | 6485-39-8 |
| Chemical Formula | C₁₂H₂₂MnO₁₄·2H₂O |
| Solubility | highly soluble in water; insoluble in ethanol |
| Storage Conditions | store in cool, dry, ventilated area protected from light |
| Shelf Life | 36 Months |
Applications & Usage
Common Applications:
used as dietary manganese supplement
texturizer
and colorant in foods and beverages
Mechanism of action:
| Parameter | Manganese Gluconate |
|---|---|
| Functional Category | Nutrient Fortificant; Color Retention Agent; Enzyme Cofactor |
| Key Ingredients | Manganese (II) Gluconate |
| Mechanism of Action | Provides a highly bioavailable source of the essential mineral manganese, a critical cofactor for enzymes involved in metabolic pathways (e.g., superoxide dismutase, arginase). As a color fixative, it forms stable complexes with pigments (e.g., in olives), preventing oxidation and degradation to maintain a uniform, dark color. |
| Application Effect in Product | Enriches foods, beverages, and supplements to meet nutritional requirements for manganese. In specific applications like ripe olives, it ensures consistent, deep black color retention and prevents fading or browning during shelf life. Supports claims related to bone health and metabolism. |
Comparison:
| Product Name | Category/Type | Key Features | Strengths (vs peers) | Weaknesses (vs peers) | Best Use Cases | Why Choose |
|---|---|---|---|---|---|---|
| Manganese Gluconate | Chelated Mineral Supplement | Manganese bound to gluconic acid, a derivative of glucose. | Good bioavailability, better than inorganic salts. Generally well-tolerated and cost-effective for a chelated form. | Lower elemental manganese content by weight compared to sulfate. May be less bioavailable than some amino acid chelates. | General daily supplementation for preventing or addressing manganese deficiency in individuals without significant absorption issues. | A balanced choice offering good absorption, tolerability, and value compared to other forms. |
| Manganese Sulfate | Inorganic Mineral Salt | Manganese bound to a sulfate ion. Often found in multivitamin/mineral formulas. | High elemental manganese content by weight. Typically the most inexpensive option. | Lower bioavailability compared to chelated forms. Can cause more gastrointestinal upset in sensitive individuals. | Cost-sensitive applications; fortification of foods and animal feed; when a higher dose of elemental manganese is required and absorption is a secondary concern. | For the lowest cost per milligram of elemental manganese. |
| Manganese Citrate | Chelated Mineral Supplement | Manganese bound to citric acid. | Excellent bioavailability, comparable or slightly superior to gluconate. Well-tolerated by the digestive system. | Generally more expensive than both sulfate and gluconate forms. | Individuals seeking a highly absorbable form with minimal gastrointestinal side effects; use in premium supplement formulations. | When high bioavailability and digestive comfort are the top priorities and cost is less of a factor. |
| Manganese Amino Acid Chelate | Chelated Mineral Supplement | Manganese bound to amino acids, such as glycine (bisglycinate) or aspartate. | Theoretically highest bioavailability due to absorption via amino acid transporters. Extremely gentle on the stomach. | Often the most expensive form of supplemental manganese. The specific chelate can vary between manufacturers. | Individuals with known malabsorption issues or very sensitive digestive systems who require manganese supplementation. | For maximum absorption and minimal digestive impact, especially for those with compromised gut function. |
Technical Documents
Available Documentation
COA and monograph available
Safety Data Sheet (SDS)
MSDS available
Certificate of Analysis (COA)
Quality assurance documentation
Technical Data Sheet
Detailed technical specifications