Magnesium Gluconate
Nutritional Enhancers
Minerals & Trace Elements
3632-91-5
C₁₂H₂₂MgO₁₄
$3.89 ~ $5.83
Food
Free sample from 100g(NF)
One unit of:25kg/barrel
One unit of:25kg/barrel
25kg/barrel
Product Info
What is Magnesium Gluconate?
Magnesium Gluconate is the magnesium salt of gluconic acid, primarily used as a highly bioavailable dietary supplement to treat or prevent magnesium deficiency and occasionally as a stabilizer in food products.
How is Magnesium Gluconate made?
| Step No. | Production Stage | Key Action | Control Point & Note |
|---|---|---|---|
| 1 | Reaction / Synthesis | React gluconic acid (or glucono-delta-lactone) with a magnesium source (e.g., magnesium carbonate) in purified water to form a magnesium gluconate solution. | Control Reaction Temperature: Maintain at 50-70°C to ensure complete reaction without degradation. Monitor pH: Adjust and monitor until pH is stable and near neutral (e.g., 6.0-7.5), indicating reaction completion. Raw Material Purity: Must use food or pharmaceutical grade raw materials. |
| 2 | Purification & Filtration | Add activated carbon to the solution to decolorize it and adsorb impurities. Filter the mixture to remove the carbon and any insoluble matter. | Filtrate Clarity: The solution must be clear and bright after filtration. Activated Carbon Dosage: Use a specified amount to avoid product loss. Filter Integrity: Ensure filter press or filtration unit is functioning correctly to prevent particle contamination. |
| 3 | Concentration | Evaporate excess water from the purified solution under vacuum to increase the concentration of magnesium gluconate, preparing it for drying. | Control Vacuum & Temperature: Evaporate at a low temperature (e.g., below 80°C) to prevent thermal degradation and discoloration. Target Density/Brix: Concentrate the solution to a pre-defined specific gravity or Brix value. |
| 4 | Spray Drying | Atomize the concentrated magnesium gluconate solution into a hot air stream, which instantly evaporates the water to form a fine powder. | Inlet/Outlet Air Temperature: This is a critical parameter that controls the final moisture content and particle characteristics. Feed Rate & Atomizer Speed: Must be precisely controlled to ensure consistent product quality and prevent wet spots or scorching. |
| 5 | Drying | Perform a final drying step on the powder, often in a fluid bed dryer, to achieve the final moisture specification. | Loss on Drying (LOD): The product must be dried until the moisture content is within the specified range (e.g., 3.0% - 12.0%). Drying Temperature: Use a moderate temperature to avoid damaging the product. |
| 6 | Sieving / Sizing | Pass the dried powder through a vibrating screen or sieve to break any agglomerates and ensure a uniform particle size distribution. | Screen Mesh Size: Select the appropriate mesh to meet the required particle size specification. Screen Integrity: Regularly inspect screens for any breaks or damage to prevent contamination. |
| 7 | Blending & Homogenization | Combine material from the batch in a large blender to ensure the entire lot is homogeneous. | Blending Time: Mix for a validated, specific duration to guarantee batch uniformity. Sample for Uniformity: Take samples from multiple locations in the blender to verify homogeneity. |
| 8 | Final Testing & Packaging | Sample the final blended product for full quality control analysis. Upon approval, package the product into clean, sealed, and correctly labeled containers. | Full Specification Analysis: Must meet all chemical (e.g., Assay, Heavy Metals) and microbiological specifications. Packaging Integrity: Use approved packaging material and ensure containers are sealed properly to prevent moisture ingress and contamination. Label Control: Verify 100% accuracy of labels, including product name, lot number, and expiry date. |
Technical Specifications
| CAS Number | 3632-91-5 |
| Chemical Formula | C₁₂H₂₂MgO₁₄ |
| Solubility | highly soluble in water (~1 g/mL at 25 °C); insoluble in ethanol |
| Storage Conditions | store in cool, dry, ventilated area, protect from moisture |
| Shelf Life | 36 Months |
Applications & Usage
Common Applications:
magnesium supplementation in foods
beverages
dairy
flour
nutritional products
Mechanism of action:
| Parameter | Magnesium Gluconate |
|---|---|
| Functional Category | Nutrient Fortificant; Firming Agent; Sequestrant |
| Key Ingredients | Magnesium Gluconate (Magnesium salt of gluconic acid) |
| Mechanism of Action | Provides bioavailable magnesium for nutritional fortification. The divalent magnesium ion (Mg2+) cross-links with anionic polysaccharides like pectin, forming stable magnesium pectate complexes that reinforce cell wall structure. It also acts as a sequestrant, binding metallic ions to prevent off-flavors and improve product stability. |
| Application Effect in Product | Enriches products with magnesium for nutritional claims. Maintains firmness and crisp texture in processed fruits and vegetables. Masks bitter notes and acts as a flavor modifier in beverages and confections. Prevents discoloration by chelating trace metals. |
Comparison:
| Product Name | Category/Type | Key Features | Strengths (vs peers) | Weaknesses (vs peers) | Best Use Cases | Why Choose |
|---|---|---|---|---|---|---|
| Magnesium Gluconate | Organic Magnesium Salt | Magnesium bound to gluconic acid; moderate bioavailability. | Very gentle on the digestive system; low incidence of diarrhea. | Lower elemental magnesium content by weight, requiring larger or more pills. Less studied for specific benefits. | General supplementation for individuals with sensitive stomachs or those who experience side effects from other forms. | You need a gentle, well-tolerated option for daily supplementation without digestive upset. |
| Magnesium Citrate | Organic Magnesium Salt | Magnesium bound to citric acid; good bioavailability and solubility. | Cost-effective, highly bioavailable, and widely available. | Well-known for its osmotic laxative effect, which can be undesirable for some users. | Correcting magnesium deficiency efficiently; relieving constipation. | You want an effective, affordable form and can tolerate or desire its laxative side effect. |
| Magnesium Glycinate | Amino Acid Chelate | Magnesium bound to the amino acid glycine; very high bioavailability. | Excellent absorption with virtually no laxative effect. Glycine may have a calming effect. | Typically more expensive than citrate or oxide. | Supplementing for deficiency without digestive issues; supporting sleep, calm, and anxiety reduction. | You prioritize maximum absorption and gentleness on the stomach, especially for sleep or relaxation benefits. |
| Magnesium Oxide | Inorganic Magnesium Salt | High percentage of elemental magnesium by weight. | Inexpensive; small pill size for the amount of elemental magnesium delivered. | Very poor bioavailability (estimated ~4%); strong laxative effect. | Use as an antacid for heartburn or as a short-term, potent laxative. Not ideal for correcting systemic deficiency. | You need a low-cost antacid or a strong laxative, not an efficient way to raise magnesium levels in the body. |
| Magnesium L-Threonate | Patented Magnesium Chelate | Specifically designed to cross the blood-brain barrier. | Uniquely effective at increasing magnesium concentrations in the brain. | Significantly more expensive than all other common forms; lower elemental magnesium content. | Supporting cognitive functions, memory, and overall brain health. | Your primary goal is to target brain health, and cost is not a major concern. |
| Magnesium Malate | Organic Magnesium Salt | Magnesium bound to malic acid; good bioavailability. | Well-absorbed; malic acid is involved in cellular energy production (Krebs cycle). | Can be more expensive than citrate or oxide. Less common in stores. | Addressing muscle pain, fatigue, or conditions like fibromyalgia; general supplementation. | You are seeking benefits for both magnesium levels and cellular energy or muscle function. |
Technical Documents
Available Documentation
COA, TDS, monograph available
Safety Data Sheet (SDS)
MSDS available
Certificate of Analysis (COA)
Quality assurance documentation
Technical Data Sheet
Detailed technical specifications