Ascorbyl Palmitate
Antioxidants
Nutritional Enhancers
Vitamins
137-66-6
E304
C₂₂H₃₈O₇
$26.68 ~ $40.02
Food
Free sample from 100g(NF)
One unit of:25kg/carton
One unit of:25kg/carton
500 g/pack
Certifications & Compliance
RSPO-MB certificate
Product Info
What is Ascorbyl Palmitate?
Ascorbyl Palmitate is a fat-soluble ester of Vitamin C used as an antioxidant to stabilize oils and fats, preventing rancidity and extending the shelf life of food products.
How is Ascorbyl Palmitate made?
| Step No. | Production Stage | Key Action | Control Point & Note |
|---|---|---|---|
| 1 | Raw Material Preparation | Weighing and charging L-Ascorbic Acid and Palmitic Acid into the reaction vessel. | Note: All raw materials must meet pre-defined purity specifications (e.g., USP/FCC grade). Accurate weighing is critical for stoichiometric balance. |
| 2 | Esterification (Synthesis) | Adding a strong acid catalyst (e.g., concentrated Sulfuric Acid) to the reactants and heating the mixture under vacuum. | Control Point: The reaction temperature (e.g., 55-65°C) and vacuum level are strictly controlled to drive the reaction forward by removing the water byproduct. Reaction progress is monitored by sampling. |
| 3 | Neutralization | Cooling the reaction mass and adding a neutralizing agent (e.g., Sodium Carbonate solution) to neutralize the acid catalyst. | Control Point: The mixture's pH is carefully adjusted to a specific range (e.g., 6.0-7.0) to stop the reaction and precipitate the crude product. This step is crucial for catalyst removal. |
| 4 | Crude Product Isolation & Washing | Filtering the neutralized slurry to separate the crude Ascorbyl Palmitate, followed by washing with purified water. | Control Point: Washing removes residual salts (e.g., sodium sulfate) and other water-soluble impurities. The conductivity of the wash water filtrate is monitored to ensure sufficient purity. |
| 5 | Recrystallization | Dissolving the crude product in a hot solvent (e.g., Isopropanol or Ethanol) and then allowing it to cool slowly to form pure crystals. | Note: This is a key purification step. The rate of cooling influences crystal size and purity. The solvent must be of high purity to avoid introducing contaminants. |
| 6 | Filtration & Separation | Separating the purified crystals from the solvent (mother liquor) using a centrifuge or filter. | Control Point: Ensures efficient separation of the pure product. The mother liquor, containing most of the remaining impurities, is drained away. |
| 7 | Drying | Drying the wet crystalline product in a vacuum oven at a controlled temperature. | Control Point: Drying temperature and vacuum level are managed to prevent thermal degradation and ensure residual solvent levels are below the acceptable limits defined by pharmacopeial standards. |
| 8 | Sieving & Blending | Sieving the dried powder through a specific mesh screen to achieve a uniform particle size. | Note: This step ensures the final product has consistent physical properties for downstream applications. The product may be blended for lot homogeneity. |
| 9 | Final Quality Control & Packaging | Sampling the final batch for full specification testing (e.g., Assay, Purity, Heavy Metals) and packaging into sealed, light-resistant containers. | Control Point: The product is only released after passing all quality tests. Packaging is done in a controlled environment to protect against moisture, light, and contamination. |
Technical Specifications
| CAS Number | 137-66-6 |
| Chemical Formula | C₂₂H₃₈O₇ |
| Solubility | Very slightly soluble in water; freely soluble in alcohol & oils |
| Storage Conditions | Store 2–8 °C, cool, dry, protect from light |
| Shelf Life | 24 Months |
Applications & Usage
Common Applications:
Used as antioxidant/preservative in foods
pharmaceuticals
cosmetics
Mechanism of action:
| Parameter | Ascorbyl Palmitate |
|---|---|
| Functional Category | Antioxidant; Nutrient Fortification (Vitamin C Source); Emulsifier |
| Key Ingredients | Ascorbyl Palmitate (Ester of L-Ascorbic Acid and Palmitic Acid) |
| Mechanism of Action | Functions as a lipophilic (fat-soluble) antioxidant. The ascorbyl moiety donates a hydrogen atom to quench lipid free radicals, terminating oxidative chain reactions. The palmitate tail anchors the molecule within fats, oils, and cell membranes, effectively protecting lipids from peroxidation where water-soluble antioxidants cannot penetrate. |
| Application Effect in Product | Inhibits the onset of oxidative rancidity in oils, fats, and fried products; preserves the stability of fat-soluble vitamins (A, D, E) and carotenoids; prevents color fading in high-fat systems; extends the shelf life of products like potato chips, vegetable oils, dressings, and processed meats. |
Comparison:
| Product Name | Category/Type | Key Features | Strengths (vs peers) | Weaknesses (vs peers) | Best Use Cases | Why Choose |
|---|---|---|---|---|---|---|
| Ascorbyl Palmitate | Fat-Soluble Vitamin C Ester | Ester of ascorbic acid and palmitic acid; antioxidant. | More stable than L-Ascorbic Acid in air. Mixes well with fats and oils. Cost-effective. | Lower biological activity and skin penetration compared to other derivatives. Conversion to ascorbic acid in skin is inefficient. | Preserving oils, fats, and anhydrous cosmetic formulas. Basic antioxidant support in oil-based products. | To provide antioxidant stability to an oil-based or water-free product on a budget. |
| L-Ascorbic Acid | Pure Water-Soluble Vitamin C | The most biologically active and researched form of Vitamin C. | Highest potency for collagen synthesis and brightening. Fast acting. | Extremely unstable; degrades quickly with exposure to air, light, and water. Can cause skin irritation. Requires low pH to be effective. | High-potency, fast-acting treatment serums for users with resilient skin. | For maximum, scientifically-proven Vitamin C benefits when stability and potential irritation are not primary concerns. |
| Tetrahexyldecyl Ascorbate (THDA) | Fat-Soluble Vitamin C Ester | A highly stable, oil-soluble derivative known for excellent skin penetration. | Very stable. Penetrates skin deeply. Less irritating than L-Ascorbic Acid. Potent antioxidant and collagen-boosting effects. | Significantly more expensive than other forms. | Premium anti-aging serums and creams, especially oil-based or emulsion formulas targeting deep wrinkles and hyperpigmentation. | For a potent, stable, and deeply penetrating oil-soluble option with low irritation potential. |
| Sodium Ascorbyl Phosphate (SAP) | Water-Soluble Vitamin C Derivative | A stable sodium salt of ascorbic acid; converts to ascorbic acid in the skin. | Very stable at neutral pH. Gentle on skin. Has known anti-acne and antimicrobial benefits. | Less potent than L-Ascorbic Acid; reliant on conversion within the skin. | Daily serums for sensitive or acne-prone skin. Brightening products for general use. | For a gentle, stable, water-based Vitamin C that is also effective for managing breakouts. |
| Magnesium Ascorbyl Phosphate (MAP) | Water-Soluble Vitamin C Derivative | A stable form of Vitamin C known for its hydrating properties. | Extremely stable and one of the least irritating derivatives. Effective for skin hydration and brightening at a near-neutral pH. | Less potent for collagen synthesis compared to L-Ascorbic Acid. Less researched than other forms. | Moisturizers and serums for dry, sensitive skin where hydration and gentle brightening are key. | For a very gentle, hydrating, and stable form of Vitamin C, especially for sensitive or dry skin types. |
Technical Documents
Available Documentation
Technical documentation & COA available
Safety Data Sheet (SDS)
Yes
Certificate of Analysis (COA)
Quality assurance documentation
Technical Data Sheet
Detailed technical specifications