D‑Ribose
Nutritional Enhancers
Sweeteners
50‑69‑1
C₅H₁₀O₅
$10.58 ~ $15.87
Food
Free sample from 100g(NF)
One unit of:25kg/barrel
One unit of:25kg/barrel
25kg/barrel
Product Info
What is D‑Ribose?
D-Ribose is a naturally occurring five-carbon sugar essential for cellular energy production (ATP) and is primarily used as a dietary supplement to support cardiac function and reduce muscle fatigue.
How is D‑Ribose made?
| Step No. | Production Stage | Key Action | Control Point & Note |
|---|---|---|---|
| 1 | Fermentation | Culture a selected strain of bacteria (e.g., Bacillus subtilis) in a sterile, nutrient-rich medium. The bacteria consume a carbon source (like glucose) and convert it into D-Ribose. | Control Point: Strict control of pH, temperature, dissolved oxygen, and nutrient feed rate is essential for optimal yield. Note: The bacterial strain is typically a genetically modified organism (GMO) specifically engineered for high-level D-Ribose production. |
| 2 | Cell Separation | Separate the bacterial biomass from the fermentation broth, which now contains the dissolved D-Ribose. | Control Point: Ensure complete removal of cells without causing them to break open (lysis), which would release impurities. Note: This is achieved using centrifugation or microfiltration. |
| 3 | Initial Purification | Remove soluble impurities such as proteins, other organic acids, and pigments from the cell-free broth. | Control Point: Monitor the effectiveness of filtration and chromatography columns. Note: This multi-stage step often involves activated carbon treatment for decolorization and ion-exchange chromatography to remove charged molecules. |
| 4 | Concentration | Remove excess water from the purified broth to create a concentrated D-Ribose syrup. | Control Point: Control the temperature and vacuum level to prevent caramelization or thermal degradation of the sugar. Note: Typically performed in a multi-effect or falling film evaporator. |
| 5 | Crystallization | Induce the formation of solid D-Ribose crystals from the supersaturated syrup by carefully controlling cooling and agitation. | Control Point: The cooling rate, agitation speed, and seed crystal addition are critical for achieving high purity and desired crystal size. Note: This is a major purification step, as impurities remain in the liquid phase (mother liquor). |
| 6 | Crystal Separation & Washing | Separate the D-Ribose crystals from the mother liquor using a centrifuge. The collected crystals are then washed with purified water. | Control Point: Monitor centrifuge speed and wash water volume to maximize purity while minimizing product loss. Note: Washing removes any residual impurities adhering to the crystal surface. |
| 7 | Drying | Dry the washed crystals to reduce the moisture content to the final specification level. | Control Point: Maintain precise drying temperature and airflow to prevent clumping or discoloration. Final moisture content must be below the specified limit (e.g., <0.5%). Note: A fluidized bed dryer is commonly used for efficient and uniform drying. |
| 8 | Sieving & Packaging | Sieve the dried crystals to ensure a uniform particle size, then package the final product into sealed, food-grade containers. | Control Point: Verify sieve mesh size and ensure packaging environment is clean and dry to prevent contamination. Note: Final QC tests for purity (assay), identity, heavy metals, and microbial content are performed before release. |
Technical Specifications
| CAS Number | 50‑69‑1 |
| Chemical Formula | C₅H₁₀O₅ |
| Solubility | 100 g/L at 25 °C |
| Storage Conditions | keep cool dry place, avoid moisture |
| Shelf Life | 24 Months |
Applications & Usage
Common Applications:
food additive
health supplements
pharmaceutical intermediate
Mechanism of action:
| Parameter | D‑Ribose |
|---|---|
| Functional Category | Nutrient; Flavor Enhancer; Browning Agent (Maillard Reaction Precursor) |
| Key Ingredients | D-Ribose (a pentose monosaccharide) |
| Mechanism of Action | Acts as a metabolic precursor for adenosine triphosphate (ATP) synthesis, supporting cellular energy functions. As a highly reactive pentose sugar, it readily participates in the Maillard reaction with amino acids upon heating, forming a complex array of flavor compounds (e.g., pyrazines) and melanoidin pigments. |
| Application Effect in Product | Accelerated browning and color development in baked goods, batters, and meats. Generation of desirable savory, roasted, and meaty flavor profiles. Used in nutritional supplements and energy drinks for its role in cellular energy metabolism. |
Comparison:
| Product Name | Category/Type | Key Features | Strengths (vs peers) | Weaknesses (vs peers) | Best Use Cases | Why Choose |
|---|---|---|---|---|---|---|
| D-Ribose | Monosaccharide Supplement | A 5-carbon sugar that is a structural component of ATP (adenosine triphosphate), the primary energy molecule of the cell. | Directly contributes to the ATP pool for rapid energy restoration; bypasses slower energy production pathways. | Less studied for raw power output compared to creatine; may cause transient hypoglycemia in sensitive individuals. | Recovering cellular energy after intense exertion; supporting cardiovascular energy demands; managing chronic fatigue. | For direct, foundational support of the cellular energy structure (ATP) and rapid energy recovery. |
| Creatine Monohydrate | Amino Acid Derivative | Increases intramuscular phosphocreatine stores, which helps rapidly regenerate ATP during short, intense bursts of activity. | Extensively researched and proven to increase strength, power output, and lean muscle mass. Very cost-effective. | Primarily benefits anaerobic, high-intensity exercise; can cause water retention and GI distress in some users. | Weightlifting, sprinting, and other sports requiring explosive power; increasing muscle hypertrophy. | When the primary goal is a proven increase in strength, power, and performance in short-duration, high-intensity activities. |
| Coenzyme Q10 (CoQ10) | Vitamin-like Compound | A crucial component of the mitochondrial electron transport chain, which generates the vast majority of cellular ATP. Also a potent antioxidant. | Supports overall mitochondrial efficiency and cardiovascular health; provides significant antioxidant protection. | Benefits for athletic performance are less direct and immediate; generally more expensive. | Supporting heart health, especially for those on statins; general mitochondrial health and anti-aging; reducing oxidative stress. | For long-term, foundational support of cellular energy production efficiency and antioxidant protection, especially for the heart. |
| L-Carnitine | Amino Acid Derivative | Facilitates the transport of fatty acids into the mitochondria to be used as an energy source. | Directly supports fat metabolism for energy production; may aid in recovery and reduce muscle soreness. | Efficacy for performance and fat loss is often modest and dependent on individual status; less impact on ATP regeneration than creatine. | Endurance exercise to enhance fat utilization; supporting post-exercise recovery; individuals with potential carnitine deficiency. | To specifically improve the body's ability to use fat as a fuel source during exercise. |
| Caffeine | Central Nervous System Stimulant | Blocks adenosine receptors, leading to increased alertness, reduced perception of fatigue, and enhanced focus. | Fast-acting and highly effective at increasing perceived energy, focus, and endurance performance. | Does not create cellular energy, only masks fatigue; can disrupt sleep, cause anxiety, and lead to tolerance. | Pre-workout for an immediate boost in energy and concentration; overcoming short-term mental or physical fatigue. | For a rapid, perceptible increase in alertness and performance when masking fatigue is the primary goal. |
Technical Documents
Available Documentation
COA and technical data sheet available
Safety Data Sheet (SDS)
MSDS available
Certificate of Analysis (COA)
Quality assurance documentation
Technical Data Sheet
Detailed technical specifications