Coenzyme Q10
Nutritional Enhancers
Antioxidants
303-98-0
C₅₉H₉₀O₄
$208.33 ~ $312.50
Food
Free sample from 100g(NF)
One unit of:1kg/bag 25kg/carton
One unit of:1kg/bag 25kg/carton
1kg/bag
25kg/carton
Product Info
What is Coenzyme Q10?
Coenzyme Q10 is a naturally occurring, fat-soluble vitamin-like antioxidant used extensively in dietary supplements and functional foods to support energy metabolism and cardiovascular health.
How is Coenzyme Q10 made?
| Step No. | Production Stage | Key Action | Control Point & Note |
|---|---|---|---|
| 1 | Fermentation | Cultivate a specific microorganism strain in a sterile, nutrient-rich broth to produce Coenzyme Q10 intracellularly. | Control Point: Maintain strict sterile conditions to prevent contamination. Monitor and control pH, temperature, and dissolved oxygen levels precisely. Note: The purity and productivity of the microbial strain are fundamental to the entire process. |
| 2 | Cell Harvesting | Separate the microbial cells containing CoQ10 from the liquid fermentation broth. | Control Point: Use high-efficiency methods like centrifugation or microfiltration. Note: The goal is to collect a concentrated cell paste with minimal loss of biomass. |
| 3 | Extraction | Break open the harvested cells (lysis) and use a solvent to extract the crude CoQ10 from the cell mass. | Control Point: Choice of an effective, food-grade solvent (e.g., ethanol or hexane). Temperature and duration of extraction must be controlled to maximize yield. Note: CoQ10 is sensitive to light and oxidation; the process should be protected. |
| 4 | Purification | Remove impurities such as lipids, water, and other cellular components from the crude CoQ10 extract. | Control Point: Column chromatography is a critical step to separate CoQ10 from structurally similar by-products, achieving high purity. Note: This is often a multi-stage process to remove different types of impurities. |
| 5 | Crystallization | Dissolve the purified CoQ10 in a hot solvent and then cool the solution to form pure, solid crystals. | Control Point: The cooling rate and degree of agitation are controlled to determine crystal size and purity. Note: This step significantly enhances the purity of the final product, resulting in a bright yellow-orange powder. |
| 6 | Drying | Wash the crystals with a cold solvent to remove any remaining impurities and then dry them to remove all moisture and residual solvents. | Control Point: Drying must be conducted under vacuum at low temperatures to prevent thermal degradation. Final residual solvent levels must meet strict specifications (e.g., USP/EP). |
| 7 | Milling & Sieving | Mill the dried crystals into a fine powder and pass it through sieves to achieve a uniform particle size. | Control Point: The particle size distribution is a key specification for product bioavailability and downstream formulation. Note: The process must be controlled to prevent heat buildup and contamination. |
| 8 | Quality Control & Packaging | Perform final analytical testing on the finished powder and package it into sealed, protective containers. | Control Point: Test for identity and purity (assay by HPLC), heavy metals, microbial contamination, and residual solvents. Note: Package in airtight, light-proof containers, often flushed with nitrogen, to ensure stability. |
Technical Specifications
| CAS Number | 303-98-0 |
| Chemical Formula | C₅₉H₉₀O₄ |
| Solubility | insoluble in water; soluble in diethyl ether; slight in ethanol |
| Storage Conditions | store in cool, dark, dry place |
| Shelf Life | 24 Months |
Applications & Usage
Common Applications:
dietary supplements
cosmetics
functional foods
Mechanism of action:
| Parameter | Coenzyme Q10 |
|---|---|
| Functional Category | Antioxidant; Bioactive Compound; Fat-Soluble Nutrient |
| Key Ingredients | Ubiquinone (also known as Ubidecarenone) |
| Mechanism of Action | Acts as a critical coenzyme in the mitochondrial electron transport chain, facilitating aerobic cellular respiration and ATP production. Functions as a potent lipid-soluble antioxidant, directly neutralizing free radicals and regenerating other antioxidants like Vitamin E (α-tocopherol) to protect cell membranes from oxidative damage. |
| Application Effect in Product | Enhances nutritional profile of functional foods and dietary supplements; protects lipid-based ingredients (e.g., oils, emulsions) from oxidation, extending shelf life; helps maintain color and flavor stability in susceptible products; supports energy metabolism and cardiovascular health claims. |
Comparison:
| Product Name | Category/Type | Key Features | Strengths (vs peers) | Weaknesses (vs peers) | Best Use Cases | Why Choose |
|---|---|---|---|---|---|---|
| Coenzyme Q10 | Vitamin-like Compound, Antioxidant | Essential for cellular ATP (energy) production; fat-soluble antioxidant; supports heart, liver, and kidney function. | Direct and critical role in mitochondrial energy cycle; extensive research for cardiovascular benefits, especially for statin users. | Lower bioavailability in its standard (ubiquinone) form; ubiquinol form is effective but more expensive. | Supporting cardiovascular health; increasing cellular energy; mitigating statin side effects; general antioxidant support. | For foundational support of cellular energy in high-demand organs like the heart. |
| PQQ (Pyrroloquinoline quinone) | Redox Cofactor, Nootropic | Promotes mitochondrial biogenesis (creation of new mitochondria); potent antioxidant; neuroprotective. | Uniquely stimulates the growth of new mitochondria, not just supporting existing ones; highly synergistic with CoQ10. | Less human research compared to CoQ10; not as central to the ATP production chain itself. | Enhancing cognitive function; long-term mitochondrial health and anti-aging; nerve cell protection. | To build new cellular powerhouses (mitochondria), especially for cognitive and longevity goals. |
| Alpha-Lipoic Acid (ALA) | Universal Antioxidant | Both water- and fat-soluble antioxidant; supports glucose metabolism; helps regenerate other antioxidants (Vitamins C, E). | Extremely versatile, functions in all parts of the cell; strong evidence for supporting nerve health and managing blood sugar. | Shorter half-life in the body; primary role is antioxidant and glucose metabolism, not direct energy production like CoQ10. | Broad-spectrum antioxidant protection; supporting healthy blood sugar levels; peripheral neuropathy support. | For comprehensive antioxidant coverage across the entire body and specific benefits for nerve health. |
| Acetyl-L-Carnitine (ALCAR) | Amino Acid Derivative | Transports fatty acids into mitochondria to be burned for energy; crosses the blood-brain barrier to support cognitive function. | Directly facilitates the use of fat for energy; significant and well-researched nootropic (brain-boosting) effects. | Role is specific to fatty acid transport, less of a broad energy cycle component or antioxidant than CoQ10. | Improving mental focus and energy; supporting fat metabolism for fuel; nerve function support. | To specifically enhance energy production from fats and for targeted neurological and cognitive support. |
| Resveratrol | Polyphenol, Antioxidant | Potent antioxidant and anti-inflammatory; activates sirtuin pathways linked to longevity; supports cardiovascular health. | Provides unique anti-aging benefits by activating specific longevity genes (SIRT1); strong anti-inflammatory properties. | Generally has low bioavailability; benefits are less focused on direct, immediate energy production. | Anti-aging protocols; reducing inflammation; supporting metabolic and cardiovascular health. | For benefits related to longevity pathways, inflammation, and vascular health, rather than just mitochondrial energy. |
Technical Documents
Available Documentation
certificate of analysis provided
Safety Data Sheet (SDS)
SDS available
Certificate of Analysis (COA)
Quality assurance documentation
Technical Data Sheet
Detailed technical specifications