L-Tyrosine
One unit of:25kg/barrel
Product Info
What is L-Tyrosine?
L-Tyrosine is a non-essential amino acid used in the food and supplement industry primarily as a nutritional additive to support protein synthesis and as a precursor for neurotransmitter production to aid cognitive function.
How is L-Tyrosine made?
| Step No. | Production Stage | Key Action | Control Point & Note |
|---|---|---|---|
| 1 | Fermentation | Cultivate a specific microbial strain (e.g., engineered E. coli or Corynebacterium glutamicum) in a sterile, nutrient-rich liquid medium. | Control Points: Sterility of the medium and equipment is paramount. The medium composition (carbon source, nitrogen, precursors), pH, temperature, and dissolved oxygen levels must be precisely controlled for optimal yield. |
| 2 | Cell Separation | Separate the microbial cells (biomass) from the L-Tyrosine-rich fermentation broth. | Control Points: Efficiency of the separation method, typically centrifugation or microfiltration, is key. The goal is to obtain a clear broth with minimal loss of dissolved L-Tyrosine. |
| 3 | Ion-Exchange Chromatography | Pass the clarified broth through an ion-exchange resin column to selectively bind and isolate L-Tyrosine from salts, sugars, and other impurities. | Control Points: The pH of the broth must be adjusted for optimal binding. The composition and flow rate of the eluting solution are critical for releasing a pure, concentrated L-Tyrosine fraction. |
| 4 | Decolorization & Concentration | Treat the purified L-Tyrosine solution with activated carbon to remove color impurities, then concentrate the solution by evaporating water under vacuum. | Control Points: Use of food-grade activated carbon. Concentration must occur at a low temperature under vacuum to prevent thermal degradation and discoloration of the product. |
| 5 | Crystallization | Induce crystallization by carefully cooling the concentrated, pure L-Tyrosine solution. | Control Points: The cooling rate and final temperature are crucial for forming pure crystals of the desired size and maximizing the yield. Agitation speed is also controlled. |
| 6 | Crystal Harvesting & Washing | Separate the L-Tyrosine crystals from the mother liquor using a centrifuge, followed by washing the crystals with purified water. | Control Points: Washing is done with cold, deionized water to remove surface impurities without significantly re-dissolving the product. Centrifuge must effectively dewater the crystal cake. |
| 7 | Drying & Sieving | Dry the washed crystals in a vacuum dryer to remove all residual moisture, then sieve the final powder to ensure a uniform particle size. | Control Points: The drying temperature must be kept low (e.g., below 80°C) to prevent degradation. The final moisture content is a critical specification (e.g., <0.5%). Sieve mesh size determines final product granularity. |
| 8 | Quality Control & Packaging | Perform comprehensive analysis on the final powder to ensure it meets all specifications (e.g., purity, heavy metals, microbial limits). Package into sealed, clean containers. | Control Points: Final product must conform to relevant standards (e.g., USP, EP, FCC). Packaging must be done in a controlled environment to prevent contamination and moisture uptake. |
Technical Specifications
| CAS Number | 60-18-4 |
| Chemical Formula | C₉H₁₁NO₃ |
| Solubility | Water soluble ~0.38–0.45 g/L at 25 °C; soluble in hot alcohol & dilute alkali/acid; insoluble in ether |
| Storage Conditions | Cool, dry, <30 °C; avoid direct light and moisture |
| Shelf Life | 24 Months |
Applications & Usage
Common Applications:
Mechanism of action:
| Parameter | L-Tyrosine |
|---|---|
| Functional Category | Nutritional Fortificant; Flavor Precursor |
| Key Ingredients | L-Tyrosine (C₉H₁₁NO₃) |
| Mechanism of Action | Acts as a building block for proteins, supplementing the nutritional profile of foods like infant formula or medical nutritionals. Serves as a biochemical precursor for neurotransmitters (dopamine, norepinephrine) and the pigment melanin. Undergoes enzymatic and chemical reactions (e.g., Maillard reaction) during food processing and aging to generate key aromatic and flavor compounds. |
| Application Effect in Product | Enriches the amino acid content in dietary supplements, infant formulas, and functional foods. Contributes to the development of characteristic savory and aged flavor notes in cheeses and cured meats. Formation of visible tyrosine crystals on aged cheeses (e.g., Parmesan, Gruyère), indicating proper maturation. |
Comparison:
| Product Name | Category/Type | Key Features | Strengths (vs peers) | Weaknesses (vs peers) | Best Use Cases | Why Choose |
|---|---|---|---|---|---|---|
| L-Tyrosine | Amino Acid / Nootropic | Direct precursor to dopamine, norepinephrine, and epinephrine. | Well-researched for replenishing neurotransmitters and improving cognitive function specifically under acute stress. | Effects are minimal in non-stressed individuals. Can compete with other amino acids for absorption. | Enhancing focus and mental performance during high-pressure situations like exams, deadlines, or sleep deprivation. | For reliable cognitive support directly tied to stressful performance demands. |
| N-Acetyl L-Tyrosine (NALT) | Amino Acid Derivative | An acetylated, more water-soluble form of L-Tyrosine. | Superior water solubility may offer easier mixing and potentially faster absorption for some users. | Conversion to Tyrosine in the body is reportedly inefficient, meaning higher doses may be needed. Less clinical evidence than L-Tyrosine. | As a soluble alternative to L-Tyrosine for cognitive support during stress. | If you prioritize solubility or respond better to this form than standard L-Tyrosine. |
| L-Theanine | Amino Acid / Nootropic | Promotes alpha brain waves, creating a state of calm alertness. | Reduces anxiety and stress without causing drowsiness. Synergizes perfectly with caffeine to smooth out its jittery effects. | Does not directly replenish stress-depleted catecholamines like Tyrosine does. Milder focus effect. | Improving focus for creative or relaxed tasks, reducing caffeine side effects, and promoting general relaxation. | For a non-stimulatory boost in focus and calm, or to pair with caffeine. |
| Rhodiola Rosea | Adaptogenic Herb | Standardized for rosavins and salidroside; helps modulate the body's stress response system. | Combats both mental and physical fatigue from chronic stress. Provides broad, systemic stress resistance. | Effects build over time; less suited for immediate, on-demand focus. Efficacy can vary by extract quality. | Managing long-term stress, burnout, and persistent fatigue. Improving mental and physical endurance. | For holistic, long-term stress management and fatigue reduction. |
| Caffeine | Stimulant | Blocks adenosine receptors in the brain, preventing drowsiness and increasing alertness. | Fast-acting, powerful, and highly effective at increasing wakefulness and concentration. Widely available. | Can cause anxiety, jitters, and a subsequent crash. Tolerance develops quickly. Does not support neurotransmitter production. | Immediate energy boost, overcoming drowsiness, pre-workout stimulation, and short-term alertness enhancement. | For a potent, fast, and short-acting boost in energy and vigilance. |
| Alpha-GPC | Choline Compound | A highly bioavailable source of choline, a precursor to the neurotransmitter acetylcholine. | Directly supports the cholinergic system, which is crucial for memory, learning, and muscle contraction. | Does not target dopamine/norepinephrine pathways, making it less effective for acute stress-related cognitive decline. | Supporting long-term memory formation, learning capacity, and overall brain health. | To specifically target memory and learning functions via the acetylcholine pathway. |
Technical Documents
Available Documentation
COA, MSDS, technical dossier
Safety Data Sheet (SDS)
Provided
Certificate of Analysis (COA)
Quality assurance documentation
Technical Data Sheet
Detailed technical specifications