L-Lysine
Amino Acids
Nutritional Enhancers
56-87-1
C₆H₁₄N₂O₂
$13.93 ~ $20.89
Food
Free sample from 100g(NF)
One unit of:25kg/drum
One unit of:25kg/drum
25kg/drum
Product Info
What is L-Lysine?
L-Lysine is an essential amino acid widely utilized as a nutritional supplement and food fortifier to ensure adequate protein synthesis, particularly in balancing livestock and poultry feed.
How is L-Lysine made?
| Step No. | Production Stage | Key Action | Control Point & Note |
|---|---|---|---|
| 1 | Medium Preparation & Sterilization | Prepare a nutrient-rich medium (carbon source like glucose, nitrogen source like ammonia) for the bacteria. Sterilize the medium using high-pressure steam to eliminate all contaminants. | Sterilization temperature and time (e.g., 121°C for 30 mins) are critical to prevent contamination. The precise composition of the medium directly impacts the final yield. |
| 2 | Seed Culture Development | Inoculate a small batch of sterile medium with a pure strain of Corynebacterium glutamicum. Allow it to grow into a robust and active starter culture. | Strict aseptic (sterile) conditions must be maintained to prevent contamination. The health and density of the seed culture are vital for a successful production run. |
| 3 | Fermentation | Transfer the seed culture to a large, industrial-scale fermenter containing the sterilized medium. The microorganisms consume the nutrients and synthesize L-Lysine over several days. | This is the core synthesis step. Key parameters like pH, temperature, dissolved oxygen, and nutrient feed rate must be continuously monitored and controlled for optimal production. |
| 4 | Harvesting & Cell Separation | Once fermentation is complete, harvest the entire broth. Separate the solid bacterial cells from the liquid broth (which contains the dissolved L-Lysine) using centrifugation or microfiltration. | The efficiency of separation is key to maximizing the recovery of the L-Lysine solution. Incomplete separation leads to product loss in the discarded cell mass. |
| 5 | Purification (Ion Exchange) | Pass the clarified broth through a cation-exchange chromatography column. L-Lysine binds to the resin, while impurities are washed away. L-Lysine is then selectively eluted. | Control of pH and flow rates during loading and elution is crucial for achieving high purity. This step removes salts, residual sugars, and other amino acids. |
| 6 | Concentration & Crystallization | Concentrate the purified L-Lysine solution using vacuum evaporation. Induce crystallization, typically as L-Lysine Hydrochloride (HCl), by cooling and adjusting the pH. | The rate of cooling and final pH are key factors that determine the size and purity of the crystals. Vacuum evaporation prevents thermal degradation of the product. |
| 7 | Drying | Separate the wet crystals from the remaining liquid (mother liquor) via centrifugation. Dry the crystals in a controlled dryer (e.g., fluidized bed dryer) to a specific moisture content. | Drying temperature and time must be carefully controlled to prevent product degradation and ensure the final moisture content is within specification (e.g., <1.0%). |
| 8 | Sieving & Packaging | Sieve the dried L-Lysine HCl to achieve a uniform particle size distribution. Package the final product into sealed, labeled containers in a clean, controlled environment. | The correct sieve mesh size must be used to meet product specifications. The packaging environment must have low humidity to prevent moisture absorption. Final Quality Control analysis is performed before release. |
Technical Specifications
| CAS Number | 56-87-1 |
| Chemical Formula | C₆H₁₄N₂O₂ |
| Solubility | Highly soluble in water (~0.1 g/mL); insoluble in ethanol, ether, acetone |
| Storage Conditions | Cool, dry, protected from moisture |
| Shelf Life | 12 Months |
Applications & Usage
Common Applications:
Food (protein supplement
emulsion stabilizer)
feed additive
dietary supplements
pharmaceuticals
Mechanism of action:
| Parameter | L-Lysine |
|---|---|
| Functional Category | Nutrient Fortifier; Maillard Browning Agent; Flavor Enhancer. |
| Key Ingredients | L-lysine hydrochloride (or other food-grade L-lysine salt). |
| Mechanism of Action | Supplements the essential amino acid profile of foods, particularly in cereal-based products, to improve protein quality (protein complementation). The free epsilon-amino group acts as a potent reactant with reducing sugars, accelerating the Maillard reaction to generate melanoidin pigments (browning) and complex savory flavor compounds. |
| Application Effect in Product | Increased nutritional value (e.g., PDCAAS) in bread, pasta, and plant-based foods. Enhanced crust color and browning in baked goods. Development of savory, roasted flavor notes in seasonings, snacks, and processed meats. Prevents protein quality degradation during thermal processing. |
Comparison:
| Product Name | Category/Type | Key Features | Strengths (vs peers) | Weaknesses (vs peers) | Best Use Cases | Why Choose |
|---|---|---|---|---|---|---|
| L-Lysine | Essential Amino Acid | Required for protein synthesis, collagen formation, and calcium absorption. Competes with arginine for cellular uptake. | Inexpensive, widely studied for HSV, directly antagonizes arginine which is required for herpes virus replication. | Less effective if dietary arginine intake is very high. High doses can cause GI distress. Limited broad-spectrum antiviral action. | Preventing and reducing the severity/duration of herpes simplex (cold sore) outbreaks. Supporting skin and connective tissue health. | For a direct, competitive biological mechanism to suppress HSV replication, especially when diet is high in arginine (nuts, chocolate). |
| L-Arginine | Conditionally Essential Amino Acid | Precursor to nitric oxide (NO), important for vasodilation, circulation, and wound healing. | Improves blood flow, supports cardiovascular health and exercise performance. | Can promote and worsen herpes virus replication and outbreaks in susceptible individuals by competing with lysine. | Supporting cardiovascular health, improving athletic performance (pump), and managing erectile dysfunction. | Choose for circulatory and performance benefits; AVOID if prone to herpes or cold sores. |
| Monolaurin | Fatty Acid Derivative | A monoglyceride derived from lauric acid (found in coconut oil). Believed to disrupt the lipid envelopes of viruses and bacteria. | Offers broad-spectrum antimicrobial support beyond just HSV. Not dependent on arginine/lysine balance. | Less specific research for HSV compared to L-Lysine. Mechanism is disruptive rather than inhibitory. | General immune support against various lipid-coated pathogens (e.g., flu, EBV, HSV) and some bacteria. | For broad-spectrum immune defense that targets the physical structure of pathogens, not just a single replication pathway. |
| Lemon Balm (Melissa officinalis) | Herbal Supplement | Contains polyphenols (e.g., rosmarinic acid) with antiviral and calming properties. Available as oral supplement or topical cream. | Dual action: antiviral and anxiolytic (calming). Clinically shown to be effective topically for healing cold sores. | Potency can vary significantly between products. May cause drowsiness or interact with thyroid medications. | Topical treatment of active cold sores, reducing outbreak frequency, and managing stress that can trigger outbreaks. | For a natural, herbal option with proven topical effectiveness and the added benefit of stress reduction. |
Technical Documents
Available Documentation
COA, MSDS, technical data
Safety Data Sheet (SDS)
Provided
Certificate of Analysis (COA)
Quality assurance documentation
Technical Data Sheet
Detailed technical specifications